Lifestyle and environment and transgenerational health in Nigeria
Birth weight is a factor of increased health risk for infants and young children, and has also been associated to the risk of NCDs in adult life. Many of the determinants of birth weight are related to maternal suboptimal nutrition and infants’ deficiency of some essential trace elements, and also to maternal environmental exposures. Very low birth weight infants are particularly susceptible to deficiencies or toxicity of trace elements, due to their rapid growth, relatively low mineral stores at birth, poor absorption, excess intestinal and renal losses and high vulnerability to oxidative stress with implications in the pathogenesis of the major complications of prematurity including respiratory distress syndrome, necrotizing enterocolitis, chronic lung disease, retinopathy of prematurity and intraventricular hemorrhage.
Sustainable food safety (diet and foods that minimize transgenerational dietary exposure) targets appropriate nutritional intervention and food safety campaigns devoted to women in childbearing age and younger. Further to the effect of nutrients and contaminants, novel scientific findings demonstrate the role of factors like, e.g. the gut microbioma, in the failure of physiological functions regulating excretions of nutrients and other risk factors.
The project identifies specific interventions to improve health in pre, peri, post conceptional phases and protect newborns from increased risks of NCDs in adulthood.